Research workbench
YENB/RHS2 complex
Analyse YENB/RHS2 complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5KIS
- Type
- protein
- Length
- 2,121 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Yenb; RHS2
- UniProt
- B6A880
- Ligands
- CA, NA, CL
- Pockets
- 20 · best druggability 0.80
Structure
x-ray diffraction · 2 distinct chains · 9% helix, 41% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Yenb | protein | 1446 | 11% helix, 39% strand | B6A880 |
| B | RHS2 | protein | 675 | 7% helix, 47% strand | — |
Ligands and binding sites
- CA · Calcium ion · metal · 2 copies · chains A, B
- NA · Sodium ion · metal · 2 copies · chains A, B
- CL · Chloride ion · ion · 4 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
20 pockets found on a 1 Å grid, 18 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 874 | 0.80 | 0.82 | 96 | empty |
| 2 | 261 | 0.79 | 0.91 | 42 | empty |
| 3 | 439 | 0.70 | 0.81 | 40 | empty |
| 4 | 615 | 0.70 | 0.78 | 56 | empty |
| 5 | 383 | 0.69 | 0.81 | 46 | empty |
Interfaces
1 interface between chains.
- A–B · 4015 Ų buried · 58 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B6A880
- Elsewhere: RCSB PDB 5KIS · PDBe 5KIS · UniProt B6A880
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