Research workbench
Fragment of NITRATE/NITRITE sensor histidine kinase narq (wt) in asymmetric holo state
Analyse Fragment of NITRATE/NITRITE sensor histidine kinase narq (wt) in asymmetric… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5JEF
- Type
- protein
- Length
- 441 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- NITRATE/NITRITE sensor protein narq
- EC
- 2.7.13.3
- UniProt
- P27896
- Ligands
- LFA, NO3
- Pockets
- 5 · best druggability 0.60
Structure
x-ray diffraction · 2 distinct chains · 83% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NITRATE/NITRITE sensor protein narq (EC 2.7.13.3) | protein | 219 | 83% helix, 0% strand | P27896 |
| B | NITRATE/NITRITE sensor protein narq (EC 2.7.13.3) | protein | 222 | 82% helix, 0% strand | P27896 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 94 | 0.60 | 0.87 | 23 | empty |
| 2 | 76 | 0.49 | 0.83 | 17 | empty |
| 3 | 133 | 0.39 | 0.74 | 19 | empty |
| 4 | 114 | 0.35 | 0.73 | 18 | empty |
| 5 | 56 | 0.34 | 0.78 | 19 | empty |
Interfaces
1 interface between chains.
- A–B · 3145 Ų buried · 16 hydrogen bonds · protein-protein
Compared structures
- 5JEF · Fragment of nitrate/nitrite sensor histidine kinase NarQ (WT) in asymmetric holo state · the same entry in another collection · chain A against A, TM-score 1.00
- P27896 · AlphaFold monomer V2.0 prediction for NITRATE/NITRITE sensor protein narq (P27896) · a predicted model of the same protein · chain A against A, TM-score 0.86
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P27896
- Elsewhere: RCSB PDB 5JEF · PDBe 5JEF · UniProt P27896
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.