Research workbench
Leut T354H mutant in the outward-oriented, na+-free return state
Analyse Leut T354H mutant in the outward-oriented, na+-free return state in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5JAG
- Type
- protein
- Length
- 496 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transporter
- UniProt
- O67854
- Pockets
- 3 · best druggability 0.75
Structure
x-ray diffraction · 1 distinct chain · 77% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transporter | protein | 496 | 77% helix, 2% strand | O67854 |
Ligands and binding sites
- BOG · octyl beta-D-glucopyranoside · additive · 7 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 631 | 0.75 | 0.81 | 70 | BOG |
| 2 | 87 | 0.36 | 0.75 | 14 | empty |
| 3 | 54 | 0.28 | 0.73 | 10 | empty |
Compared structures
- 5JAG · LeuT T354H mutant in the outward-oriented, Na+-free Return State · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O67854
- Elsewhere: RCSB PDB 5JAG · PDBe 5JAG · UniProt O67854
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