Research workbench
Crystal structure of the cysteine desulfurase sufs of bacillus subtilis
Analyse Crystal structure of the cysteine desulfurase sufs of bacillus subtilis in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5J8Q
- Type
- protein
- Length
- 413 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cysteine desulfurase sufs
- EC
- 2.8.1.7
- UniProt
- O32164
- Ligands
- PLP, ALA
- Pockets
- 4 · best druggability 0.45
Structure
x-ray diffraction · 1 distinct chain · 46% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cysteine desulfurase sufs (EC 2.8.1.7) | protein | 413 | 46% helix, 17% strand | O32164 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 124 | 0.45 | 0.78 | 29 | PLP, ALA |
| 2 | 62 | 0.43 | 0.81 | 13 | empty |
| 3 | 72 | 0.42 | 0.80 | 20 | empty |
| 4 | 54 | 0.41 | 0.82 | 14 | empty |
Modifications
Observed in the structure: 1 cofactor, 1 modified (pyridoxal phosphate Schiff base, oxidation).
Compared structures
- 5J8Q · Crystal Structure of the Cysteine Desulfurase SufS of Bacillus subtilis · the same entry in another collection · chain A against A, TM-score 1.00
- O32164 · AlphaFold monomer V2.0 prediction for cysteine desulfurase sufs (O32164) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O32164
- Elsewhere: RCSB PDB 5J8Q · PDBe 5J8Q · UniProt O32164
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