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Crystal structure of human NEIL1, free protein

Analyse Crystal structure of human NEIL1, free protein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5ITQ
Type: protein
Length: 286 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Endonuclease 8-like 1
EC: 3.2.2.-, 4.2.99.18
UniProt: Q96FI4
Pockets: 2 · best druggability 0.56

Structure

x-ray diffraction · 1 distinct chain · 31% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Endonuclease 8-like 1 (EC 3.2.2.-, 4.2.99.18)	protein	286	31% helix, 23% strand	Q96FI4

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	273	0.56	0.77	26	empty
2	69	0.30	0.73	10	empty

Compared structures

5ITQ · Crystal Structure of Human NEIL1, Free Protein · the same entry in another collection · chain A against A, TM-score 1.00
Q96FI4 · AlphaFold monomer V2.0 prediction for endonuclease 8-like 1 (Q96FI4) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q96FI4
Elsewhere: RCSB PDB 5ITQ · PDBe 5ITQ · UniProt Q96FI4

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