Research workbench
Crystal structure of extra cellular CU/ZN superoxide dismutase from onchocerca volvulus at 1.5 ångström; insight into novel binding site and new inhibitors
Analyse Crystal structure of extra cellular CU/ZN superoxide dismutase from onchocerca… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5IN2
- Type
- protein
- Length
- 156 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Extracellular superoxide dismutase [cu-zn]
- EC
- 1.15.1.1
- UniProt
- Q07449
- Ligands
- ZN, CU, SO4, CL, AZI
Structure
x-ray diffraction · 1 distinct chain · 8% helix, 40% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Extracellular superoxide dismutase [cu-zn] (EC 1.15.1.1) | protein | 156 | 8% helix, 40% strand | Q07449 |
Ligands and binding sites
- ZN · Zinc ion · metal · chains A
- CU · Copper (II) ion · metal · chains A
- SO4 · Sulfate ion · ion · chains A
- CL · Chloride ion · ion · chains A
- AZI · Azide ion · ion · chains A
- GOL · Glycerol · additive · chains A
- PGE · Triethylene glycol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 5IN2 · Crystal structure of extra cellular Cu/Zn Superoxide Dismutase from Onchocerca volvulus… · the same entry in another collection · chain A against A, TM-score 1.00
- Q07449 · AlphaFold monomer V2.0 prediction for extracellular superoxide dismutase [cu-zn] (Q07449) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q07449
- Elsewhere: RCSB PDB 5IN2 · PDBe 5IN2 · UniProt Q07449
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