Research workbench
FABP5 in complex with 6-chloro-4-phenyl-2-piperidin-1-yl-3-(1H- tetrazol-5-yl)-quinoline
Analyse FABP5 in complex with 6-chloro-4-phenyl-2-piperidin-1-yl-3-(1H… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5HZ5
- Type
- protein
- Length
- 134 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fatty acid-binding protein, epidermal
- UniProt
- Q01469
- Ligands
- 65X, SO4
- Pockets
- 1 · best druggability 0.84
Structure
x-ray diffraction · 1 distinct chain · 15% helix, 58% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Fatty acid-binding protein, epidermal | protein | 134 | 15% helix, 58% strand | Q01469 |
Ligands and binding sites
- 65X · 6-chloro-4-phenyl-2-(piperidin-1-yl)-3-(1H-tetrazol-5-yl)quinoline · ligand · chains A
- SO4 · Sulfate ion · ion · chains A
- DMS · Dimethyl sulfoxide · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 310 | 0.84 | 0.94 | 36 | 65X |
Compared structures
- 5HZ5 · FABP5 in complex with 6-Chloro-4-phenyl-2-piperidin-1-yl-3-(1H-tetrazol-5-yl)-quinoline · the same entry in another collection · chain A against A, TM-score 1.00
- Q01469 · AlphaFold monomer V2.0 prediction for fatty acid-binding protein 5 (Q01469) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q01469
- Elsewhere: RCSB PDB 5HZ5 · PDBe 5HZ5 · UniProt Q01469
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