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Crystal structure of a repeat protein with two protein a-DHR14 repeat modules

Analyse Crystal structure of a repeat protein with two protein a-DHR14 repeat modules in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5H7C
Type: protein
Length: 797 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Immunoglobulin G-binding protein a, DHR14
UniProt: P38507
Pockets: 6 · best druggability 0.71

Structure

x-ray diffraction · 2 distinct chains · 84% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Immunoglobulin G-binding protein a, DHR14	protein	400	84% helix, 0% strand	P38507
C	Immunoglobulin G-binding protein a, DHR14	protein	397	84% helix, 0% strand	P38507

Pockets

6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1072	0.71	0.75	72	empty
2	93	0.36	0.75	21	empty
3	59	0.32	0.76	15	empty
4	57	0.29	0.75	15	empty
5	55	0.28	0.74	13	empty

Interfaces

1 interface between chains.

A–C · 108 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

5H7C · Crystal structure of a repeat protein with two Protein A-DHR14 repeat modules · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P38507
Elsewhere: RCSB PDB 5H7C · PDBe 5H7C · UniProt P38507

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