UniProt P38507
Immunoglobulin G-binding protein A (P38507)
Immunoglobulin G-binding protein A (UniProt P38507), EC 4.1.1.-: 79 experimental structures on GenesisL1, 2 ligands bound, 27 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P38507
- Protein
- Immunoglobulin G-binding protein A
- EC
- 4.1.1.-
- Experimental structures
- 79
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 27 · 4 records with a druggable one
Structures
79 records of P38507 in the MolNFT archive: 79 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1BDC | Staphylococcus aureus protein a, immunoglobulin-binding B domain, NMR, 10 structures | solution nmr | A | — | — |
| 1BDC | Staphylococcus aureus protein a, immunoglobulin-binding B domain, NMR, 10 structures | solution nmr | A | — | — |
| 1BDD | Staphylococcus aureus protein a, immunoglobulin-binding B domain, NMR, minimized average structure | solution nmr | A | — | — |
| 1BDD | Staphylococcus aureus protein a, immunoglobulin-binding B domain, NMR, minimized average structure | solution nmr | A | — | — |
| 1EDI | Staphylococcal protein a E-domain (180), NMR, minimized average structure | solution nmr | A | — | — |
| 1EDI | Staphylococcal protein a E-domain (180), NMR, minimized average structure | solution nmr | A | — | — |
| 1EDJ | Staphylococcal protein a E-domain (180), NMR, 20 structures | solution nmr | A | — | — |
| 1EDJ | Staphylococcal protein a E-domain (180), NMR, 20 structures | solution nmr | A | — | — |
| 1EDK | Staphylococcal protein a E-domain (-60), NMR, minimized average structure | solution nmr | A | — | — |
| 1EDK | Staphylococcal protein a E-domain (-60), NMR, minimized average structure | solution nmr | A | — | — |
| 1EDL | Staphylococcal protein a E-domain (-60), NMR, 22 structures | solution nmr | A | — | — |
| 1EDL | Staphylococcal protein a E-domain (-60), NMR, 22 structures | solution nmr | A | — | — |
| 1LP1 | Protein Z in complex with an in vitro selected affibody | x-ray diffraction | B | — | — |
| 1LP1 | Protein Z in complex with an in vitro selected affibody | x-ray diffraction | B | — | — |
| 1Q2N | REFINED Solution NMR structure of the Z domain of STAPHYLOCOCCAL PROTEIN A | solution nmr | A | — | — |
| 1Q2N | Refined solution NMR structure of the Z domain of staphylococcal protein a | solution nmr | A | — | — |
| 1SS1 | Staphylococcal protein a, B-domain, Y15W mutant, NMR, 25 structures | solution nmr | A | — | — |
| 1SS1 | Staphylococcal protein a, B-domain, Y15W mutant, NMR, 25 structures | solution nmr | A | — | — |
| 2JWD | protein A | solution nmr | A | — | — |
| 2JWD | PROTEIN A | solution nmr | A | — | — |
| 2M5A | Protein A binding by an engineered Affibody molecule | solution nmr | A | — | — |
| 2M5A | Protein a binding by an engineered affibody molecule | solution nmr | A | — | — |
| 2SPZ | Staphylococcal protein a, Z-domain, NMR, 10 structures | solution nmr | A | — | — |
| 2SPZ | Staphylococcal protein a, Z-domain, NMR, 10 structures | solution nmr | A | — | — |
| 3MZW | HER2 extracelluar region with affinity matured 3-helix affibody ZHER2:342 | x-ray diffraction | B | — | — |
| 3MZW | HER2 extracelluar region with affinity matured 3-helix affibody ZHER2:342 | x-ray diffraction | B | — | — |
| 4NPD | High-resolution structure of C domain of staphylococcal protein A at cryogenic temperature | x-ray diffraction | A | — | — |
| 4NPD | High-resolution structure of C domain of staphylococcal protein a at cryogenic temperature | x-ray diffraction | A | — | — |
| 4NPE | High-resolution structure of C domain of staphylococcal protein A at room temperature | x-ray diffraction | A | — | — |
| 4NPE | High-resolution structure of C domain of staphylococcal protein a at room temperature | x-ray diffraction | A | — | — |
| 4NPF | High-resolution structure of two tandem B domains of staphylococcal protein A connected by the… | x-ray diffraction | Y, X | — | — |
| 4NPF | High-resolution structure of two tandem B domains of staphylococcal protein a connected by the… | x-ray diffraction | Y, X | — | — |
| 4WWI | Crystal structure of the C domain of staphylococcal protein A in complex with the Fc fragment of… | x-ray diffraction | A, B, C | — | — |
| 4WWI | Crystal structure of the C domain of staphylococcal protein a in complex with the Fc fragment of… | x-ray diffraction | A, B, C | — | — |
| 4ZMD | C domain of staphylococcal protein A mutant - Q9W | x-ray diffraction | A, B | — | — |
| 4ZMD | C domain of staphylococcal protein a mutant - Q9W | x-ray diffraction | A, B | — | — |
| 4ZNC | Fc fragment of human IgG in complex with the C domain of staphylococcal protein a mutant - Q9W | x-ray diffraction | A, B, C | — | — |
| 5CBN | Fusion protein of MBP3-16 and B4 domain of protein a from staphylococcal aureus with chemical… | x-ray diffraction | A | — | — |
| 5CBO | Fusion protein of MBP3-16 and B4 domain of protein a from staphylococcal aureus | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | — | — |
| 5COC | Fusion protein of human calmodulin and B4 domain of protein a from staphylococcal aureus | x-ray diffraction | A | — | — |
| 5EWX | Fusion protein of T4 lysozyme and B4 domain of protein a from staphylococcal aureus with chemical… | x-ray diffraction | A, B | — | — |
| 5H75 | Crystal structure of the MrsD-Protein A fusion protein | x-ray diffraction | A, B, C, D | FAD | 8 (best 0.76) |
| 5H75 | Crystal structure of the mrsd-protein a fusion protein | x-ray diffraction | A, B, C, D | — | — |
| 5H76 | Crystal structure of the darpin-protein a fusion protein | x-ray diffraction | A, B, C | — | — |
| 5H77 | Crystal structure of the PKA-protein a fusion protein | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | — | — |
| 5H79 | Crystal structure of a repeat protein with three protein a repeat module | x-ray diffraction | D, C | — | — |
| 5H7A | Crystal structure of a repeat protein with four Protein A repeat module | x-ray diffraction | C, A, D, B, E, F, G, H, I, J, K, L | — | — |
| 5H7A | Crystal structure of a repeat protein with four protein a repeat module | x-ray diffraction | C, A, D, B, E, F, G, H, I, J, K, L | — | — |
| 5H7B | Crystal structure of a repeat protein with five protein a repeat modules | x-ray diffraction | A, B | — | — |
| 5H7C | Crystal structure of a repeat protein with two protein a-DHR14 repeat modules | x-ray diffraction | A, C | — | — |
| 5H7D | Crystal structure of the ygjg-protein a-ZPA963-calmodulin complex | x-ray diffraction | A, B, C, D, I, J, M, N | — | — |
| 5X3F | Crystal structure of the ygjg-protein a-ZPA963-PKA catalytic domain | x-ray diffraction | A | — | — |
| 5XBY | Crystal structure of the PKA-protein a fusion protein (end-to-end fusion) | x-ray diffraction | A, B, C, D | — | — |
| 6KRV | Crystal structure of mouse IGG2B Fc complexed with B domain of protein a | x-ray diffraction | D | — | — |
| 7EOY | Engineered hepatitis B virus core antigen T=3 | electron microscopy | B, C, A | — | — |
| 7EP6 | Engineered hepatitis B virus core antigen T=4 | electron microscopy | A, B, C, D | — | — |
| 7FDJ | Engineered hepatitis B virus core antigen with short linker T=4 | electron microscopy | A, B, D, C | — | — |
| 7NHA | 1918 H1N1 viral influenza polymerase heterotrimer - endonuclease and priming loop ordered (CLASS2A) | electron microscopy | C | — | — |
| 7NHC | 1918 H1N1 viral influenza polymerase heterotrimer - endonuclease ordered (CLASS2B) | electron microscopy | C | — | — |
| 7NHX | 1918 H1N1 Viral influenza polymerase heterotrimer - full transcriptase (Class1) | electron microscopy | C | — | — |
19 records more on the page itself.
Ligands
Experiment against prediction
- 5XBY chain A against the predicted model P13861: TM-score 0.96, RMSD 0.39 Å
- 8JXS chain C against the predicted model P0AEX9: TM-score 0.77, RMSD 0.81 Å
- 5H77 chain I against the predicted model P13861: TM-score 0.53, RMSD 1.69 Å
- 5H77 chain K against the predicted model P13861: TM-score 0.52, RMSD 1.96 Å
- 5H77 chain B against the predicted model P13861: TM-score 0.51, RMSD 1.34 Å
- 5H77 chain H against the predicted model P13861: TM-score 0.51, RMSD 1.85 Å
- 5H77 chain J against the predicted model P13861: TM-score 0.51, RMSD 1.58 Å
- 5H77 chain G against the predicted model P13861: TM-score 0.50, RMSD 3.38 Å
- 5H77 chain L against the predicted model P13861: TM-score 0.50, RMSD 3.90 Å
- 5XBY chain D against the predicted model P13861: TM-score 0.49, RMSD 3.93 Å
Elsewhere
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