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Solution structure of the C-terminal SH3 domain of P67PHOX complexed with the C-terminal tail region of P47PHOX

Analyse Solution structure of the C-terminal SH3 domain of P67PHOX complexed with the… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
1K4U
Type
protein
Length
94 residues
Chains
2
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Phagocyte NADPH oxidase subunit P67PHOX; Phagocyte NADPH oxidase subunit P47PHOX
UniProt
P19878, P14598

Structure

solution nmr · 2 distinct chains · 16% helix, 23% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
SPhagocyte NADPH oxidase subunit P67PHOXprotein625% helix, 35% strandP19878
PPhagocyte NADPH oxidase subunit P47PHOXprotein3238% helix, 0% strandP14598

Interfaces

1 interface between chains.

  • S–P · 812 Ų buried · 4 hydrogen bonds · protein-protein

Compared structures

  • 1K4U · Solution structure of the C-terminal SH3 domain of p67phox complexed with the C-terminal… · the same entry in another collection · chain S against S, TM-score 1.00
  • P19878 · AlphaFold monomer V2.0 prediction for neutrophil cytosol factor 2 (P19878) · a predicted model of the same protein · chain S against A, TM-score 0.78
  • P14598 · AlphaFold monomer V2.0 prediction for neutrophil cytosol factor 1 (P14598) · a predicted model of the same protein · chain P against A, TM-score 0.39

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