Research workbench
The crystal structure of the cps-6 H148A/F122A
Analyse The crystal structure of the cps-6 H148A/F122A in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5GKC
- Type
- protein
- Length
- 481 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Endonuclease G, mitochondrial
- EC
- 3.1.30.-
- UniProt
- Q95NM6
- Pockets
- 5 · best druggability 0.71
Structure
x-ray diffraction · 2 distinct chains · 25% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Endonuclease G, mitochondrial (EC 3.1.30.-) | protein | 238 | 26% helix, 32% strand | Q95NM6 |
| B | Endonuclease G, mitochondrial (EC 3.1.30.-) | protein | 243 | 25% helix, 31% strand | Q95NM6 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 207 | 0.71 | 0.87 | 42 | empty |
| 2 | 109 | 0.42 | 0.77 | 18 | empty |
| 3 | 73 | 0.36 | 0.77 | 17 | empty |
| 4 | 98 | 0.33 | 0.73 | 18 | empty |
| 5 | 69 | 0.28 | 0.73 | 12 | empty |
Interfaces
1 interface between chains.
- A–B · 1535 Ų buried · 23 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q95NM6
- Elsewhere: RCSB PDB 5GKC · PDBe 5GKC · UniProt Q95NM6
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.