UniProt Q95NM6
Endonuclease G, mitochondrial (Q95NM6)
Endonuclease G, mitochondrial (UniProt Q95NM6), EC 3.1.30.-: 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q95NM6
- Protein
- Endonuclease G, mitochondrial
- EC
- 3.1.30.-
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 7 · 1 record with a druggable one
Structures
9 records of Q95NM6 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3S5B | Crystal Structure of CED-3 Protease Suppressor-6 (CPS-6) from Caenorhabditis elegans | x-ray diffraction | A, B | — | — |
| 3S5B | Crystal structure of ced-3 protease suppressor-6 (cps-6) from caenorhabditis elegans | x-ray diffraction | A, B | — | — |
| 4QN0 | Crystal structure of the CPS-6 mutant Q130K | x-ray diffraction | A, B, C, D | — | — |
| 4QN0 | Crystal structure of the cps-6 mutant Q130K | x-ray diffraction | A, B, C, D | — | — |
| 5GKC | The crystal structure of the CPS-6 H148A/F122A | x-ray diffraction | A, B | — | — |
| 5GKC | The crystal structure of the cps-6 H148A/F122A | x-ray diffraction | A, B | — | — |
| 5GKP | Crystal structure of the EndoG worm homologue CPS-6 H148A/F122A in complex with DNA | x-ray diffraction | A, B | MG | 6 (best 0.73) |
| 5GKP | Crystal structure of the endog worm homologue cps-6 H148A/F122A in complex with DNA | x-ray diffraction | A, B | — | — |
| Q95NM6 | AlphaFold monomer V2.0 prediction for endonuclease G, mitochondrial (Q95NM6) | predicted | A | — | 1 (best 0.39) |
Ligands
- MG · Magnesium ion · in 1 record
Experiment against prediction
- 4QN0 chain A against the predicted model Q95NM6: TM-score 1.00, RMSD 0.27 Å
- 4QN0 chain A against the predicted model Q95NM6: TM-score 1.00, RMSD 0.27 Å
- 5GKP chain A against the predicted model Q95NM6: TM-score 1.00, RMSD 0.35 Å
- 5GKP chain A against the predicted model Q95NM6: TM-score 1.00, RMSD 0.35 Å
- 4QN0 chain B against the predicted model Q95NM6: TM-score 1.00, RMSD 0.37 Å
- 4QN0 chain B against the predicted model Q95NM6: TM-score 1.00, RMSD 0.37 Å
- 5GKC chain A against the predicted model Q95NM6: TM-score 1.00, RMSD 0.39 Å
- 5GKC chain A against the predicted model Q95NM6: TM-score 1.00, RMSD 0.39 Å
- 3S5B chain A against the predicted model Q95NM6: TM-score 1.00, RMSD 0.52 Å
- 3S5B chain A against the predicted model Q95NM6: TM-score 1.00, RMSD 0.52 Å
Elsewhere
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