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The crystal structure of light-driven chloride pump clr (T102D) mutant at pH 4.5.

Analyse The crystal structure of light-driven chloride pump clr (T102D) mutant at pH… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5G2C
Type: protein
Length: 268 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Chloride pumping rhodopsin
UniProt: W8VZW3
Ligands: OLA, RET, CL
Pockets: 1 · best druggability 0.72

Structure

x-ray diffraction · 1 distinct chain · 81% helix, 3% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Chloride pumping rhodopsin	protein	268	81% helix, 3% strand	W8VZW3

Ligands and binding sites

OLA · Oleic acid · ligand · 8 copies · chains A
RET · Retinal · ligand · chains A
CL · Chloride ion · ion · chains A
PEG · Di(hydroxyethyl)ether · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	129	0.72	0.91	23	RET

Modifications

Observed in the structure: 1 cofactor (retinal Schiff base).

Compared structures

5G2C · The crystal structure of light-driven chloride pump ClR (T102D) mutant at pH 4.5. · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt W8VZW3
Elsewhere: RCSB PDB 5G2C · PDBe 5G2C · UniProt W8VZW3

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