Research workbench
Structure of USP7 catalytic domain and three ubl-domains
Analyse Structure of USP7 catalytic domain and three ubl-domains in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5FWI
- Type
- protein
- Length
- 662 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ubiquitin carboxyl-terminal hydrolase 7
- EC
- 3.4.19.12
- UniProt
- Q93009
- Pockets
- 7 · best druggability 0.58
Structure
x-ray diffraction · 1 distinct chain · 30% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| C | Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) | protein | 662 | 30% helix, 29% strand | Q93009 |
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 153 | 0.58 | 0.82 | 20 | empty |
| 2 | 203 | 0.55 | 0.79 | 27 | empty |
| 3 | 112 | 0.51 | 0.81 | 17 | empty |
| 4 | 94 | 0.36 | 0.75 | 20 | empty |
| 5 | 83 | 0.33 | 0.74 | 22 | empty |
Compared structures
- 5FWI · structure of usp7 catalytic domain and three ubl-domains · the same entry in another collection · chain C against C, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q93009
- Elsewhere: RCSB PDB 5FWI · PDBe 5FWI · UniProt Q93009
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