Research workbench
Crystal structure of M. musculus protein arginine methyltransferase PRMT6 with sah at 1.65 ångströms
Analyse Crystal structure of M. musculus protein arginine methyltransferase PRMT6 with… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5FQN
- Type
- protein
- Length
- 322 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein arginine methyltransferase 6
- EC
- 2.1.1.-, 2.1.1.125
- UniProt
- Q6NZB1
- Ligands
- SAH
- Pockets
- 2 · best druggability 0.64
Structure
x-ray diffraction · 1 distinct chain · 28% helix, 37% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein arginine methyltransferase 6 (EC 2.1.1.-, 2.1.1.125) | protein | 322 | 28% helix, 37% strand | Q6NZB1 |
Ligands and binding sites
- SAH · S-adenosyl-L-homocysteine · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 337 | 0.64 | 0.79 | 37 | SAH |
| 2 | 59 | 0.48 | 0.85 | 17 | empty |
Compared structures
- 5FQN · Crystal structure of M. musculus protein arginine methyltransferase PRMT6 with SAH at… · the same entry in another collection · chain A against A, TM-score 1.00
- Q6NZB1 · AlphaFold monomer V2.0 prediction for protein arginine N-methyltransferase 6 (Q6NZB1) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6NZB1
- Elsewhere: RCSB PDB 5FQN · PDBe 5FQN · UniProt Q6NZB1
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