Research workbench
C-terminal domain of SARS-cov NSP8 complex with NSP7
Analyse C-terminal domain of SARS-cov NSP8 complex with NSP7 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5F22
- Type
- protein
- Length
- 194 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Non-structural protein 7; Non-structural protein
- UniProt
- P0C6U8, P0C6X7
- Pockets
- 2 · best druggability 0.46
Structure
x-ray diffraction · 2 distinct chains · 56% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Non-structural protein 7 | protein | 79 | 80% helix, 0% strand | P0C6U8 |
| B | Non-structural protein | protein | 115 | 39% helix, 26% strand | P0C6X7 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 86 | 0.46 | 0.81 | 15 | empty |
| 2 | 60 | 0.34 | 0.77 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 1517 Ų buried · 9 hydrogen bonds · protein-protein
Compared structures
- 5F22 · C-terminal domain of SARS-CoV nsp8 complex with nsp7 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0C6U8
- Every structure of UniProt P0C6X7
- Elsewhere: RCSB PDB 5F22 · PDBe 5F22 · UniProt P0C6U8 · UniProt P0C6X7
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