Research workbench
Crystal structure of 6-hydroxynicotinic acid 3-monooxygenase from pseudomonas putida KT2440
Analyse Crystal structure of 6-hydroxynicotinic acid 3-monooxygenase from pseudomonas… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5EOW
- Type
- protein
- Length
- 353 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 6-hydroxynicotinate 3-monooxygenase
- EC
- 1.14.13.114
- UniProt
- Q88FY2
- Ligands
- FAD
- Pockets
- 1 · best druggability 0.79
Structure
x-ray diffraction · 1 distinct chain · 36% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 6-hydroxynicotinate 3-monooxygenase (EC 1.14.13.114) | protein | 353 | 36% helix, 25% strand | Q88FY2 |
Ligands and binding sites
- FAD · Flavin-adenine dinucleotide · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 908 | 0.79 | 0.82 | 97 | FAD |
Modifications
Observed in the structure: 10 modified (engineered).
Compared structures
- 5EOW · Crystal Structure of 6-Hydroxynicotinic Acid 3-Monooxygenase from Pseudomonas putida… · the same entry in another collection · chain A against A, TM-score 1.00
- Q88FY2 · AlphaFold monomer V2.0 prediction for 6-hydroxynicotinate 3-monooxygenase (Q88FY2) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q88FY2
- Elsewhere: RCSB PDB 5EOW · PDBe 5EOW · UniProt Q88FY2
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