Research workbench
Structure of rcl-cleaved vaspin (SERPINA12)
Analyse Structure of rcl-cleaved vaspin (SERPINA12) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5EI0
- Type
- protein
- Length
- 743 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Serpin A12
- UniProt
- Q8IW75
- Pockets
- 8 · best druggability 0.73
Structure
x-ray diffraction · 2 distinct chains · 30% helix, 38% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Serpin A12 | protein | 372 | 29% helix, 37% strand | Q8IW75 |
| E | Serpin A12 | protein | 371 | 31% helix, 38% strand | Q8IW75 |
Pockets
8 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 949 | 0.73 | 0.77 | 90 | empty |
| 2 | 67 | 0.41 | 0.80 | 12 | empty |
| 3 | 113 | 0.40 | 0.75 | 21 | empty |
| 4 | 76 | 0.38 | 0.77 | 14 | empty |
| 5 | 104 | 0.38 | 0.75 | 17 | empty |
Interfaces
1 interface between chains.
- A–E · 656 Ų buried · 9 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8IW75
- Elsewhere: RCSB PDB 5EI0 · PDBe 5EI0 · UniProt Q8IW75
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