UniProt Q8IW75
Serpin A12 (Q8IW75)
Serpin A12 (UniProt Q8IW75): 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 18 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8IW75
- Protein
- Serpin A12
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 18 · 1 record with a druggable one
Structures
9 records of Q8IW75 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4IF8 | Structure Of Vaspin | x-ray diffraction | A, B | — | — |
| 4IF8 | Structure of vaspin | x-ray diffraction | A, B | — | — |
| 4Y3K | Structure of Vaspin mutant E379S | x-ray diffraction | A, B | — | — |
| 4Y3K | Structure of vaspin mutant E379S | x-ray diffraction | A, B | — | — |
| 4Y40 | Structure of Vaspin mutant D305C V383C | x-ray diffraction | A, B | SO4 | 11 (best 0.64) |
| 4Y40 | Structure of vaspin mutant D305C V383C | x-ray diffraction | A, B | — | — |
| 5EI0 | Structure of RCL-cleaved vaspin (serpinA12) | x-ray diffraction | A, E | — | — |
| 5EI0 | Structure of rcl-cleaved vaspin (SERPINA12) | x-ray diffraction | A, E | — | — |
| Q8IW75 | AlphaFold monomer V2.0 prediction for serpin A12 (Q8IW75) | predicted | A | — | 7 (best 0.41) |
Ligands
- SO4 · Sulfate ion · in 1 record
Experiment against prediction
- 4IF8 chain B against the predicted model Q8IW75: TM-score 0.98, RMSD 0.99 Å
- 4IF8 chain B against the predicted model Q8IW75: TM-score 0.98, RMSD 0.99 Å
- 4Y3K chain B against the predicted model Q8IW75: TM-score 0.98, RMSD 1.01 Å
- 4Y3K chain B against the predicted model Q8IW75: TM-score 0.98, RMSD 1.01 Å
- 4Y40 chain A against the predicted model Q8IW75: TM-score 0.98, RMSD 1.06 Å
- 4Y40 chain A against the predicted model Q8IW75: TM-score 0.98, RMSD 1.06 Å
- 4IF8 chain A against the predicted model Q8IW75: TM-score 0.98, RMSD 1.06 Å
- 4IF8 chain A against the predicted model Q8IW75: TM-score 0.98, RMSD 1.06 Å
- 4Y40 chain B against the predicted model Q8IW75: TM-score 0.98, RMSD 1.05 Å
- 4Y40 chain B against the predicted model Q8IW75: TM-score 0.98, RMSD 1.05 Å
Elsewhere
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