Research workbench
Gamma-subunit of the translation initiation factor 2 from S. solfataricus
Analyse Gamma-subunit of the translation initiation factor 2 from S. solfataricus in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5DSZ
- Type
- protein
- Length
- 815 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Translation initiation factor 2 subunit gamma
- UniProt
- Q980A5
- Pockets
- 10 · best druggability 0.69
Structure
x-ray diffraction · 2 distinct chains · 18% helix, 40% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Translation initiation factor 2 subunit gamma | protein | 408 | 18% helix, 40% strand | Q980A5 |
| B | Translation initiation factor 2 subunit gamma | protein | 407 | 18% helix, 39% strand | Q980A5 |
Pockets
10 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 707 | 0.69 | 0.77 | 72 | empty |
| 2 | 427 | 0.63 | 0.77 | 58 | empty |
| 3 | 244 | 0.63 | 0.81 | 34 | empty |
| 4 | 400 | 0.63 | 0.78 | 40 | empty |
| 5 | 291 | 0.60 | 0.79 | 43 | empty |
Interfaces
1 interface between chains.
- A–B · 623 Ų buried · 10 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 disulfide (disulfide).
Compared structures
- 5DSZ · Gamma-subunit of the translation initiation factor 2 from S. solfataricus · the same entry in another collection · chain A against A, TM-score 1.00
- Q980A5 · AlphaFold monomer V2.0 prediction for translation initiation factor 2 subunit gamma… · a predicted model of the same protein · chain B against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q980A5
- Elsewhere: RCSB PDB 5DSZ · PDBe 5DSZ · UniProt Q980A5
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.