Research workbench

Are carboxy terminii of helices coded by the local sequence or by tertiary structure contacts

Analyse Are carboxy terminii of helices coded by the local sequence or by tertiary… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1JQU
Type: protein
Length: 656 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Lysozyme
EC: 3.2.1.17
UniProt: P00720
Pockets: 6 · best druggability 0.64

Structure

x-ray diffraction · 1 distinct chain · 62% helix, 9% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D	Lysozyme (EC 3.2.1.17)	protein	164	62% helix, 9% strand	P00720

Pockets

6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	514	0.64	0.76	39	empty
2	178	0.50	0.77	19	empty
3	196	0.45	0.74	27	empty
4	138	0.42	0.75	23	empty
5	149	0.39	0.73	20	empty

Interfaces

3 interfaces between chains.

A–B · 817 Å² buried · 13 hydrogen bonds · protein-protein
B–D · 275 Å² buried · 3 hydrogen bonds · protein-protein
B–C · 126 Å² buried · 5 hydrogen bonds · protein-protein

Compared structures

1JQU · Are Carboxy Terminii of Helices Coded by the Local Sequence or by Tertiary Structure… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P00720
Elsewhere: RCSB PDB 1JQU · PDBe 1JQU · UniProt P00720

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.