Research workbench
Crystal structure of amino acids 1590-1657 of MYH7
Analyse Crystal structure of amino acids 1590-1657 of MYH7 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5CHX
- Type
- protein
- Length
- 419 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- XRCC4-MYH7-1590-1657
- UniProt
- Q13426, P12883
- Pockets
- 3 · best druggability 0.45
Structure
x-ray diffraction · 2 distinct chains · 55% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | XRCC4-MYH7-1590-1657 | protein | 210 | 55% helix, 28% strand | Q13426, P12883 |
| B | XRCC4-MYH7-1590-1657 | protein | 209 | 56% helix, 28% strand | Q13426, P12883 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 104 | 0.45 | 0.78 | 17 | empty |
| 2 | 123 | 0.44 | 0.77 | 21 | empty |
| 3 | 72 | 0.36 | 0.77 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 2942 Ų buried · 12 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 32 modified (methylation).
Compared structures
- 5CHX · Crystal Structure of amino acids 1590-1657 of MYH7 · the same entry in another collection · chain A against A, TM-score 1.00
- Q13426 · AlphaFold monomer V2.0 prediction for DNA repair protein XRCC4 (Q13426) · a predicted model of the same protein · chain A against A, TM-score 0.93
- P12883 · AlphaFold monomer V2.0 prediction for myosin-7 (P12883) · a predicted model of the same protein · chain A against A, TM-score 0.52
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13426
- Every structure of UniProt P12883
- Elsewhere: RCSB PDB 5CHX · PDBe 5CHX · UniProt Q13426 · UniProt P12883
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