UniProt P12883
Gp7-MYH7-(1526-1571) chimera protein (P12883)
Gp7-MYH7-(1526-1571) chimera protein (UniProt P12883): 36 experimental structures on GenesisL1, 1 ligand bound, 5 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P12883
- Protein
- Gp7-MYH7-(1526-1571) chimera protein
- Experimental structures
- 36
- Predicted models
- 0
- Ligands
- 1
- Pockets
- 5 · 1 record with a druggable one
Structures
36 records of P12883 in the MolNFT archive: 36 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2FXM | Structure of the human beta-myosin S2 fragment | x-ray diffraction | A, B | — | — |
| 2FXM | Structure of the human beta-myosin S2 fragment | x-ray diffraction | A, B | — | — |
| 2FXO | Structure of the human beta-myosin S2 fragment | x-ray diffraction | A, B, C, D | — | — |
| 2FXO | Structure of the human beta-myosin S2 fragment | x-ray diffraction | A, B, C, D | — | — |
| 3DTP | Tarantula heavy meromyosin obtained by flexible docking to Tarantula muscle thick filament Cryo-EM… | electron microscopy | A, B | — | — |
| 3DTP | Tarantula heavy meromyosin obtained by flexible docking to tarantula muscle thick filament cryo-EM… | electron microscopy | A, B | — | — |
| 4DB1 | Cardiac human myosin S1dC, beta isoform complexed with Mn-AMPPNP | x-ray diffraction | A, B | — | — |
| 4DB1 | Cardiac human myosin S1DC, beta isoform complexed with mn-amppnp | x-ray diffraction | A, B | — | — |
| 4P7H | Structure of Human beta-Cardiac Myosin Motor Domain::GFP chimera | x-ray diffraction | A, B | — | — |
| 4P7H | Structure of human beta-cardiac myosin motor DOMAIN::GFP chimera | x-ray diffraction | A, B | — | — |
| 4PA0 | Omecamtiv Mercarbil binding site on the Human Beta-Cardiac Myosin Motor Domain | x-ray diffraction | A, B | — | — |
| 4PA0 | Omecamtiv mercarbil binding site on the human beta-cardiac myosin motor domain | x-ray diffraction | A, B | — | — |
| 4XA1 | Crystal Structure of the coiled-coil surrounding Skip 1 of MYH7 | x-ray diffraction | A, B, C, D | — | — |
| 4XA1 | Crystal structure of the coiled-coil surrounding skip 1 of MYH7 | x-ray diffraction | A, B, C, D | — | — |
| 4XA3 | Crystal structure of the coiled-coil surrounding Skip 2 of MYH7 | x-ray diffraction | A, B | — | — |
| 4XA3 | Crystal structure of the coiled-coil surrounding skip 2 of MYH7 | x-ray diffraction | A, B | — | — |
| 4XA4 | Crystal Structure of the coiled-coil surrounding Skip 3 of MYH7 | x-ray diffraction | A, B | — | — |
| 4XA4 | Crystal structure of the coiled-coil surrounding skip 3 of MYH7 | x-ray diffraction | A, B | — | — |
| 4XA6 | Crystal Structure of the coiled-coil surrounding Skip 4 of MYH7 | x-ray diffraction | A, B, C, D | — | — |
| 4XA6 | Crystal structure of the coiled-coil surrounding skip 4 of MYH7 | x-ray diffraction | A, B, C, D | — | — |
| 5CHX | Crystal Structure of amino acids 1590-1657 of MYH7 | x-ray diffraction | A, B | — | 3 (best 0.45) |
| 5CHX | Crystal structure of amino acids 1590-1657 of MYH7 | x-ray diffraction | A, B | — | — |
| 5CJ0 | Crystal structure of amino acids 1631-1692 of MYH7 | x-ray diffraction | A, B | — | — |
| 5CJ1 | Crystal structure of the coiled coil of MYH7 residues 1526 to 1571 fused to Gp7 | x-ray diffraction | A, B, C, D, E, F, G, H | — | 2 (best 0.65) |
| 5CJ1 | Crystal structure of the coiled coil of MYH7 residues 1526 to 1571 fused to GP7 | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 5CJ4 | Crystal structure of amino acids 1562-1622 of MYH7 | x-ray diffraction | A, B, C, D | — | — |
| 5TBY | Human beta cardiac heavy meromyosin interacting-heads motif obtained by homology modeling (using… | electron microscopy | A, B | — | — |
| 5WJ7 | Crystal Structure of Amino Acids 1733-1797 of Human Beta Cardiac Myosin Fused to Xrcc4 | x-ray diffraction | A, B | — | — |
| 5WJ7 | Crystal structure of amino acids 1733-1797 of human beta cardiac myosin fused to XRCC4 | x-ray diffraction | A, B | — | — |
| 5WJB | Crystal Structure of Amino Acids 1733-1797 of Human Beta Cardiac Myosin Fused to Gp7 | x-ray diffraction | A, B, C, D | — | — |
| 5WJB | Crystal structure of amino acids 1733-1797 of human beta cardiac myosin fused to GP7 | x-ray diffraction | A, B, C, D | — | — |
| 5WLQ | Crystal Structure of Amino Acids 1677-1755 of Human Beta Cardiac Myosin Fused to Gp7 and Eb1 | x-ray diffraction | A | TMO | — |
| 5WLQ | Crystal structure of amino acids 1677-1755 of human beta cardiac myosin fused to GP7 and EB1 | x-ray diffraction | A | TMO | — |
| 5WLZ | Crystal structure of amino acids 1677-1758 of human beta cardiac myosin fused to XRCC4 | x-ray diffraction | C, D, A, B | — | — |
| 5WME | Crystal structure of amino acids 1729-1786 of human beta cardiac myosin fused to GP7 as… | x-ray diffraction | A, B, C, D | — | — |
| P12883 | AlphaFold monomer V2.0 prediction for myosin-7 (P12883) | — | — | — |
Ligands
- TMO · trimethylamine oxide · in 2 records
Experiment against prediction
- 4XA4 chain A against the predicted model Q13426: TM-score 0.95, RMSD 1.30 Å
- 4XA4 chain A against the predicted model Q13426: TM-score 0.95, RMSD 1.30 Å
- 4P7H chain A against the predicted model P42212: TM-score 0.23, RMSD 0.74 Å
- 4P7H chain A against the predicted model P42212: TM-score 0.23, RMSD 0.74 Å
- 5CHX chain A against the predicted model Q13426: TM-score 0.93, RMSD 1.73 Å
- 5CHX chain A against the predicted model Q13426: TM-score 0.93, RMSD 1.73 Å
- 4P7H chain B against the predicted model P42212: TM-score 0.23, RMSD 0.75 Å
- 4P7H chain B against the predicted model P42212: TM-score 0.23, RMSD 0.75 Å
- 4PA0 chain A against the predicted model P42212: TM-score 0.22, RMSD 0.66 Å
- 4PA0 chain A against the predicted model P42212: TM-score 0.22, RMSD 0.66 Å
Elsewhere
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