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Pseudokinase and C-terminal extension of human tribbles homolog 1

Analyse Pseudokinase and C-terminal extension of human tribbles homolog 1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5CEM
Type: protein
Length: 252 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Tribbles homolog 1
UniProt: Q96RU8
Ligands: SO4
Pockets: 1 · best druggability 0.26

Structure

x-ray diffraction · 1 distinct chain · 38% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tribbles homolog 1	protein	252	38% helix, 17% strand	Q96RU8

Ligands and binding sites

SO4 · Sulfate ion · ion · 4 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	51	0.26	0.74	14	empty

Compared structures

Q96RU8 · AlphaFold monomer V2.0 prediction for tribbles homolog 1 (Q96RU8) · a predicted model of the same protein · chain A against A, TM-score 0.89

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q96RU8
Elsewhere: RCSB PDB 5CEM · PDBe 5CEM · UniProt Q96RU8

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