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Structure of mouse clustered PCDHGA1 EC1-3

Analyse Structure of mouse clustered PCDHGA1 EC1-3 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4ZI9
Type: protein
Length: 618 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: MCG133388, isoform CRA_T
UniProt: Q91XZ0
Ligands: CA
Pockets: 6 · best druggability 0.56

Structure

x-ray diffraction · 1 distinct chain · 10% helix, 44% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	MCG133388, isoform CRA_T	protein	309	10% helix, 44% strand	Q91XZ0

Ligands and binding sites

CA · Calcium ion · metal · 12 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	302	0.56	0.76	32	empty
2	300	0.54	0.75	37	empty
3	60	0.38	0.79	14	empty
4	61	0.37	0.79	15	empty
5	64	0.34	0.77	14	empty

Interfaces

1 interface between chains.

A–B · 1263 Å² buried · 17 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

4ZI9 · Structure of mouse clustered PcdhgA1 EC1-3 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q91XZ0
Elsewhere: RCSB PDB 4ZI9 · PDBe 4ZI9 · UniProt Q91XZ0

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