Research workbench
Structural basis of lewisb antigen binding by the helicobacter pylori adhesin baba
Analyse Structural basis of lewisb antigen binding by the helicobacter pylori adhesin… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4ZH7
- Type
- protein
- Length
- 485 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Outer membrane protein-adhesin
- UniProt
- Q9ZKV2
- Ligands
- GAL, FUC, NAG
- Pockets
- 3 · best druggability 0.46
Structure
x-ray diffraction · 1 distinct chain · 52% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Outer membrane protein-adhesin | protein | 485 | 52% helix, 17% strand | Q9ZKV2 |
Ligands and binding sites
- GAL · beta-D-galactopyranose · sugar · 2 copies · chains A
- FUC · alpha-L-fucopyranose · sugar · 2 copies · chains A
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 179 | 0.46 | 0.75 | 29 | empty |
| 2 | 64 | 0.36 | 0.78 | 17 | empty |
| 3 | 55 | 0.32 | 0.77 | 18 | empty |
Modifications
Observed in the structure: 4 disulfide (disulfide).
Compared structures
- 4ZH7 · Structural basis of Lewisb antigen binding by the Helicobacter pylori adhesin BabA · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9ZKV2
- Elsewhere: RCSB PDB 4ZH7 · PDBe 4ZH7 · UniProt Q9ZKV2
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