Research workbench
Hybrid structural analysis of the ARP2/3 regulator arpin identifies its acidic tail as a primary binding epitope
Analyse Hybrid structural analysis of the ARP2/3 regulator arpin identifies its acidic… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4Z68
- Type
- protein
- Length
- 167 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tankyrase-2; Glu-ile-arg-glu-gln-gly-asp-gly-ala-glu-asp-glu
- EC
- 2.4.2.30
- UniProt
- Q9H2K2
- Ligands
- SO4
Structure
x-ray diffraction · 2 distinct chains · 49% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tankyrase-2 (EC 2.4.2.30) | protein | 155 | 52% helix, 0% strand | Q9H2K2 |
| E | Glu-ile-arg-glu-gln-gly-asp-gly-ala-glu-asp-glu | protein | 12 | 0% helix, 0% strand | — |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–E · 680 Ų buried · 17 hydrogen bonds · protein-protein
Compared structures
- 4Z68 · Hybrid structural analysis of the Arp2/3 regulator Arpin identifies its acidic tail as a… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9H2K2
- Elsewhere: RCSB PDB 4Z68 · PDBe 4Z68 · UniProt Q9H2K2
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