Research workbench
Complex of FLIM(SPOA)::FLIN fusion protein and FLIH(APAR)::T4LYSOZYME fusion protein
Analyse Complex of FLIM(SPOA)::FLIN fusion protein and FLIH(APAR)::T4LYSOZYME fusion… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4YXC
- Type
- protein
- Length
- 349 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Flagellar assembly protein H,ENDOLYSIN; Flagellar motor switch protein FLIM,FLAGELLAR…
- EC
- 3.2.1.17
- UniProt
- L5WUL9, P00720, P26418, P26419
- Pockets
- 4 · best druggability 0.55
Structure
x-ray diffraction · 2 distinct chains · 34% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Flagellar assembly protein H,ENDOLYSIN (EC 3.2.1.17) | protein | 182 | 55% helix, 9% strand | L5WUL9, P00720 |
| B | Flagellar motor switch protein FLIM,FLAGELLAR motor switch protein flin | protein | 167 | 11% helix, 52% strand | P26418, P26419 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 125 | 0.55 | 0.83 | 20 | empty |
| 2 | 182 | 0.49 | 0.77 | 28 | empty |
| 3 | 93 | 0.39 | 0.77 | 23 | empty |
| 4 | 72 | 0.38 | 0.77 | 14 | empty |
Interfaces
1 interface between chains.
- A–B · 1048 Ų buried · 9 hydrogen bonds · protein-protein
Compared structures
- 4YXC · Complex of FliM(SPOA)::FliN fusion protein and FliH(APAR)::T4lysozyme fusion protein · the same entry in another collection · chain A against A, TM-score 1.00
- P26419 · AlphaFold monomer V2.0 prediction for flagellar motor switch protein flin (P26419) · a predicted model of the same protein · chain B against A, TM-score 0.47
- P26418 · AlphaFold monomer V2.0 prediction for flagellar motor switch protein flim (P26418) · a predicted model of the same protein · chain B against A, TM-score 0.37
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt L5WUL9
- Every structure of UniProt P00720
- Every structure of UniProt P26418
- Every structure of UniProt P26419
- Elsewhere: RCSB PDB 4YXC · PDBe 4YXC · UniProt L5WUL9 · UniProt P00720 · UniProt P26418 · UniProt P26419
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