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Calcium-dependent protein kinase from eimeria tenella

Analyse Calcium-dependent protein kinase from eimeria tenella in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4YSM
Type: protein
Length: 950 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Calmodulin-like domain protein kinase
UniProt: Q3HNM4
Ligands: CA
Pockets: 17 · best druggability 0.70

Structure

x-ray diffraction · 1 distinct chain · 49% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Calmodulin-like domain protein kinase	protein	475	49% helix, 13% strand	Q3HNM4

Ligands and binding sites

CA · Calcium ion · metal · 8 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

17 pockets found on a 1 Å grid, 11 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	662	0.70	0.78	61	empty
2	571	0.70	0.79	48	empty
3	58	0.69	0.97	25	empty
4	78	0.66	0.91	14	empty
5	246	0.63	0.81	30	empty

Interfaces

1 interface between chains.

A–B · 675 Å² buried · 4 hydrogen bonds · protein-protein

Compared structures

4YSM · Calcium-Dependent Protein Kinase from Eimeria tenella · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q3HNM4
Elsewhere: RCSB PDB 4YSM · PDBe 4YSM · UniProt Q3HNM4

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