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Crystal structure of MAPK13 at inactive form

Analyse Crystal structure of MAPK13 at inactive form in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4YNO
Type: protein
Length: 342 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Mitogen-activated protein kinase 13
EC: 2.7.11.24
UniProt: O15264
Pockets: 2 · best druggability 0.66

Structure

x-ray diffraction · 1 distinct chain · 38% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Mitogen-activated protein kinase 13 (EC 2.7.11.24)	protein	342	38% helix, 16% strand	O15264

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	315	0.66	0.81	33	empty
2	55	0.27	0.74	18	empty

Compared structures

4YNO · Crystal structure of MAPK13 at INACTIVE FORM · the same entry in another collection · chain A against A, TM-score 1.00
O15264 · AlphaFold monomer V2.0 prediction for mitogen-activated protein kinase 13 (O15264) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O15264
Elsewhere: RCSB PDB 4YNO · PDBe 4YNO · UniProt O15264

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