UniProt O15264
Mitogen-activated protein kinase 13 (O15264)
Mitogen-activated protein kinase 13 (UniProt O15264): 15 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O15264
- Protein
- Mitogen-activated protein kinase 13
- Experimental structures
- 15
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 6 · 2 records with a druggable one
Structures
16 records of O15264 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3COI | Crystal structure of p38delta kinase | x-ray diffraction | A | — | — |
| 3COI | Crystal structure of P38DELTA kinase | x-ray diffraction | A | — | — |
| 4EYJ | MAPK13 Complex with inhibitor | x-ray diffraction | A | — | — |
| 4EYJ | MAPK13 complex with inhibitor | x-ray diffraction | A | — | — |
| 4EYM | MAPK13 complex with inhibitor | x-ray diffraction | A | — | — |
| 4EYM | MAPK13 complex with inhibitor | x-ray diffraction | A | — | — |
| 4MYG | MAPK13, active form | x-ray diffraction | A, B | — | — |
| 4MYG | MAPK13, active form | x-ray diffraction | A, B | — | — |
| 4YNO | Crystal structure of MAPK13 at INACTIVE FORM | x-ray diffraction | A | — | — |
| 4YNO | Crystal structure of MAPK13 at inactive form | x-ray diffraction | A | — | — |
| 5EKN | Crystal structure of MAPK13 complex with inhibitor | x-ray diffraction | A | N58 | — |
| 5EKN | Crystal structure of MAPK13 complex with inhibitor | x-ray diffraction | A | — | — |
| 5EKO | Crystal structure of MAPK13 complex with inhibitor | x-ray diffraction | A | N17 | — |
| 5EKO | Crystal structure of MAPK13 complex with inhibitor | x-ray diffraction | A | — | — |
| 8X23 | The Crystal Structure of MAPK13 from Biortus. | x-ray diffraction | A | — | 2 (best 0.66) |
| O15264 | AlphaFold monomer V2.0 prediction for mitogen-activated protein kinase 13 (O15264) | predicted | A | — | 4 (best 0.71) |
Ligands
Experiment against prediction
- 4YNO chain A against the predicted model O15264: TM-score 0.97, RMSD 1.21 Å
- 4YNO chain A against the predicted model O15264: TM-score 0.97, RMSD 1.21 Å
- 8X23 chain A against the predicted model O15264: TM-score 0.97, RMSD 1.32 Å
- 5EKN chain A against the predicted model O15264: TM-score 0.97, RMSD 1.27 Å
- 5EKN chain A against the predicted model O15264: TM-score 0.97, RMSD 1.27 Å
- 5EKO chain A against the predicted model O15264: TM-score 0.97, RMSD 1.32 Å
- 5EKO chain A against the predicted model O15264: TM-score 0.97, RMSD 1.32 Å
- 4EYM chain A against the predicted model O15264: TM-score 0.97, RMSD 1.33 Å
- 4EYM chain A against the predicted model O15264: TM-score 0.97, RMSD 1.33 Å
- 4EYJ chain A against the predicted model O15264: TM-score 0.97, RMSD 1.40 Å
Elsewhere
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