Research workbench
Aspartic proteinase SAPP2 secreted from candida parapsilosis at 0.82 a resolution.
Analyse Aspartic proteinase SAPP2 secreted from candida parapsilosis at 0.82 a… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4Y9W
- Type
- protein
- Length
- 332 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Aspartic acid endopeptidase SAPP2; Peptide
- UniProt
- G8B6Y8
- Ligands
- IVA
- Pockets
- 1 · best druggability 0.41
Structure
x-ray diffraction · 2 distinct chains · 12% helix, 49% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Aspartic acid endopeptidase SAPP2 | protein | 327 | 12% helix, 50% strand | G8B6Y8 |
| B | Peptide | protein | 5 | 0% helix, 40% strand | — |
Ligands and binding sites
- IVA · Isovaleric acid · ligand · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 155 | 0.41 | 0.73 | 28 | IVA |
Interfaces
1 interface between chains.
- A–B · 610 Ų buried · 17 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide, 2 modified, 1 covalent (disulfide, nonstandard, covalent ligand).
Compared structures
- 4Y9W · Aspartic Proteinase Sapp2 Secreted from Candida Parapsilosis at 0.82 A Resolution. · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G8B6Y8
- Elsewhere: RCSB PDB 4Y9W · PDBe 4Y9W · UniProt G8B6Y8
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.