Research workbench
Crystal structure of the chlamydomonas IFT70 and IFT52 complex
Analyse Crystal structure of the chlamydomonas IFT70 and IFT52 complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4UZY
- Type
- protein
- Length
- 674 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Flagellar associated protein; Intraflagellar transport protein IFT52
- UniProt
- A8ITN7, Q946G4
- Pockets
- 10 · best druggability 0.74
Structure
x-ray diffraction · 2 distinct chains · 69% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Flagellar associated protein | protein | 624 | 74% helix, 0% strand | A8ITN7 |
| B | Intraflagellar transport protein IFT52 | protein | 50 | 8% helix, 0% strand | Q946G4 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
10 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 545 | 0.74 | 0.81 | 40 | empty |
| 2 | 397 | 0.67 | 0.80 | 42 | empty |
| 3 | 116 | 0.50 | 0.80 | 25 | FLC |
| 4 | 201 | 0.48 | 0.75 | 26 | empty |
| 5 | 167 | 0.46 | 0.75 | 22 | empty |
Interfaces
1 interface between chains.
- A–B · 3301 Ų buried · 31 hydrogen bonds · protein-protein
Compared structures
- 4UZY · Crystal structure of the Chlamydomonas IFT70 and IFT52 complex · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A8ITN7
- Every structure of UniProt Q946G4
- Elsewhere: RCSB PDB 4UZY · PDBe 4UZY · UniProt A8ITN7 · UniProt Q946G4
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