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Crystal structure of RAP74 C-terminal domain complexed with FCP1 C- terminal peptide

Analyse Crystal structure of RAP74 C-terminal domain complexed with FCP1 C- terminal… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1J2X
Type: protein
Length: 88 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Transcription initiation factor iif, alpha subunit; RNA polymerase II ctd phosphatase
UniProt: P35269, Q9Y5B0
Ligands: ZN, SO4

Structure

x-ray diffraction · 2 distinct chains · 52% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Transcription initiation factor iif, alpha subunit	protein	70	49% helix, 16% strand	P35269
B	RNA polymerase II ctd phosphatase	protein	18	67% helix, 0% strand	Q9Y5B0

Ligands and binding sites

ZN · Zinc ion · metal · chains A
SO4 · Sulfate ion · ion · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

A–B · 682 Å² buried · 2 hydrogen bonds · protein-protein

Compared structures

1J2X · Crystal structure of RAP74 C-terminal domain complexed with FCP1 C-terminal peptide · the same entry in another collection · chain A against A, TM-score 1.00
P35269 · AlphaFold monomer V2.0 prediction for general transcription factor iif subunit 1 (P35269) · a predicted model of the same protein · chain A against A, TM-score 0.88
Q9Y5B0 · AlphaFold monomer V2.0 prediction for RNA polymerase II subunit a C-terminal domain… · a predicted model of the same protein · chain B against A, TM-score 0.63

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P35269
Every structure of UniProt Q9Y5B0
Elsewhere: RCSB PDB 1J2X · PDBe 1J2X · UniProt P35269 · UniProt Q9Y5B0

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