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Assembly principles of the unique cage formed by the ATPase rava hexamer and the lysine decarboxylase ldci decamer

Analyse Assembly principles of the unique cage formed by the ATPase rava hexamer and… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
4UPF
Type
protein
Length
784 residues
Chains
2
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Lysine decarboxylase, inducible; ATPase rava
EC
4.1.1.18, 3.6.3.1
UniProt
P0A9H3, P31473
Pockets
1 · best druggability 0.41

Structure

electron microscopy · 2 distinct chains · 0% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ALysine decarboxylase, inducible (EC 4.1.1.18)protein7100% helix, 0% strandP0A9H3
DATPase rava (EC 3.6.3.1)protein740% helix, 0% strandP31473

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11360.410.7337empty

Compared structures

  • 4UPF · Assembly principles of the unique cage formed by the ATPase RavA hexamer and the lysine… · the same entry in another collection · chain A against A, TM-score 1.00
  • P0A9H3 · AlphaFold monomer V2.0 prediction for inducible lysine decarboxylase (P0A9H3) · a predicted model of the same protein · chain A against A, TM-score 0.98
  • P31473 · AlphaFold monomer V2.0 prediction for ATPase rava (P31473) · a predicted model of the same protein · chain D against A, TM-score 0.98

Analyse

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