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Structure of leptospira interrogans lrr protein LIC11098

Analyse Structure of leptospira interrogans lrr protein LIC11098 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4U08
Type: protein
Length: 782 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: LIC11098
UniProt: Q72TC3
Ligands: ZN, CA, SO4
Pockets: 5 · best druggability 0.68

Structure

x-ray diffraction · 1 distinct chain · 23% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	LIC11098	protein	391	23% helix, 14% strand	Q72TC3

Ligands and binding sites

ZN · Zinc ion · metal · 9 copies · chains A, B
CA · Calcium ion · metal · chains A, B
SO4 · Sulfate ion · ion · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	657	0.68	0.77	86	empty
2	130	0.51	0.81	23	empty
3	110	0.49	0.81	18	empty
4	79	0.34	0.76	16	empty
5	53	0.26	0.74	14	empty

Interfaces

1 interface between chains.

A–B · 1312 Å² buried · 25 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 modified (engineered).

Compared structures

4U08 · Structure of Leptospira interrogans LRR protein LIC11098 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q72TC3
Elsewhere: RCSB PDB 4U08 · PDBe 4U08 · UniProt Q72TC3

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