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Crystal structure of a family GH18 chitinase from chromobacterium violaceum

Analyse Crystal structure of a family GH18 chitinase from chromobacterium violaceum in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4TX8
Type: protein
Length: 374 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Probable chitinase a
UniProt: Q7NTW8
Ligands: NAG, MG, CA
Pockets: 1 · best druggability 0.40

Structure

x-ray diffraction · 1 distinct chain · 29% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Probable chitinase a	protein	374	29% helix, 21% strand	Q7NTW8

Ligands and binding sites

NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · chains A
MG · Magnesium ion · metal · chains A
CA · Calcium ion · metal · chains A
FLC · Citrate anion · additive · 4 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	138	0.40	0.74	20	FLC

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

4TX8 · Crystal Structure of a Family GH18 Chitinase from Chromobacterium violaceum · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7NTW8
Elsewhere: RCSB PDB 4TX8 · PDBe 4TX8 · UniProt Q7NTW8

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