Research workbench
A novel protein fold forms an intramolecular lock to stabilize the tertiary structure of streptococcus mutans adhesin P1
Analyse A novel protein fold forms an intramolecular lock to stabilize the tertiary… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4TSH
- Type
- protein
- Length
- 606 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Surface protein adhesin
- UniProt
- C9E3B4
- Ligands
- CA, MG
- Pockets
- 1 · best druggability 0.36
Structure
x-ray diffraction · 2 distinct chains · 21% helix, 37% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Surface protein adhesin | protein | 121 | 55% helix, 14% strand | C9E3B4 |
| B | Surface protein adhesin | protein | 485 | 13% helix, 43% strand | C9E3B4 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 69 | 0.36 | 0.78 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 3309 Ų buried · 60 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 3 isopeptide (isopeptide).
Compared structures
- 4TSH · A Novel Protein Fold Forms an Intramolecular Lock to Stabilize the Tertiary Structure of… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C9E3B4
- Elsewhere: RCSB PDB 4TSH · PDBe 4TSH · UniProt C9E3B4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.