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Structure of the dirigent protein DRR206

Analyse Structure of the dirigent protein DRR206 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4REV
Type: protein
Length: 255 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Disease resistance response protein 206
UniProt: P13240
Ligands: DMI, CL
Pockets: 3 · best druggability 0.62

Structure

x-ray diffraction · 2 distinct chains · 0% helix, 64% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Disease resistance response protein 206	protein	128	0% helix, 64% strand	P13240
B	Disease resistance response protein 206	protein	127	0% helix, 63% strand	P13240

Ligands and binding sites

DMI · 2,3-dimethylimidazolium ion · ligand · chains B
CL · Chloride ion · ion · 2 copies · chains B
GOL · Glycerol · additive · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	257	0.62	0.80	24	empty
2	250	0.58	0.78	23	empty
3	202	0.55	0.78	28	empty

Interfaces

1 interface between chains.

A–B · 392 Å² buried · 3 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

4REV · Structure of the dirigent protein DRR206 · the same entry in another collection · chain A against A, TM-score 1.00
P13240 · AlphaFold monomer V2.0 prediction for disease resistance response protein 206 (P13240) · a predicted model of the same protein · chain B against A, TM-score 0.84

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Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P13240
Elsewhere: RCSB PDB 4REV · PDBe 4REV · UniProt P13240

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