Research workbench
Crystal structure of wt cgmp dependent protein kinase I alpha (pkgi alpha) leucine zipper
Analyse Crystal structure of wt cgmp dependent protein kinase I alpha (pkgi alpha)… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4R4L
- Type
- protein
- Length
- 143 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cgmp-dependent protein kinase 1
- UniProt
- Q13976
- Ligands
- SO4
Structure
x-ray diffraction · 2 distinct chains · 91% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Cgmp-dependent protein kinase 1 | protein | 47 | 91% helix, 0% strand | Q13976 |
| C | Cgmp-dependent protein kinase 1 | protein | 49 | 90% helix, 0% strand | Q13976 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
3 interfaces between chains.
- A–B · 1346 Ų buried · 6 hydrogen bonds · protein-protein
- B–C · 754 Ų buried · 11 hydrogen bonds · protein-protein
- A–C · 90 Ų buried · 0 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 4R4L · Crystal structure of wt cGMP dependent protein kinase I alpha (PKGI alpha) leucine zipper · the same entry in another collection · chain A against A, TM-score 1.00
- Q13976 · AlphaFold monomer V2.0 prediction for cgmp-dependent protein kinase 1 (Q13976) · a predicted model of the same protein · chain A against A, TM-score 0.91
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13976
- Elsewhere: RCSB PDB 4R4L · PDBe 4R4L · UniProt Q13976
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