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Interferon alpha-2A, NMR, 24 structures

Analyse Interferon alpha-2A, NMR, 24 structures in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1ITF
Type: protein
Length: 165 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Interferon alpha-2A
UniProt: P01563
Pockets: 1 · best druggability 0.54

Structure

solution nmr · 1 distinct chain · 62% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Interferon alpha-2A	protein	165	62% helix, 0% strand	P01563

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	135	0.54	0.82	26	empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

1ITF · Interferon alpha-2A, NMR, 24 structures · the same entry in another collection · chain A against A, TM-score 1.00
P01563 · AlphaFold monomer V2.0 prediction for interferon alpha-2 (P01563) · a predicted model of the same protein · chain A against A, TM-score 0.89

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P01563
Elsewhere: RCSB PDB 1ITF · PDBe 1ITF · UniProt P01563

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