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Crystal structure of acinetobacter sp. DL28 L-ribose isomerase mutant E204Q in complex with L-ribose
Analyse Crystal structure of acinetobacter sp. DL28 L-ribose isomerase mutant E204Q in… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4Q0U
- Type
- protein
- Length
- 249 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- L-ribose isomerase
- EC
- 5.3.1.-
- UniProt
- Q93UQ5
- Ligands
- Z6J, ROR, NCO, 0MK, CO
- Pockets
- 3 · best druggability 0.63
Structure
x-ray diffraction · 1 distinct chain · 17% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | L-ribose isomerase (EC 5.3.1.-) | protein | 249 | 17% helix, 27% strand | Q93UQ5 |
Ligands and binding sites
- Z6J · alpha-L-ribofuranose · ligand · 3 copies · chains A
- ROR · L-ribose · ligand · chains A
- NCO · Cobalt hexammine(iii) · ligand · chains A
- 0MK · beta-L-ribopyranose · sugar · chains A
- CO · Cobalt (II) ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 246 | 0.63 | 0.82 | 34 | empty |
| 2 | 91 | 0.33 | 0.73 | 14 | empty |
| 3 | 50 | 0.27 | 0.74 | 13 | empty |
Compared structures
- 4Q0U · Crystal structure of Acinetobacter sp. DL28 L-ribose isomerase mutant E204Q in complex… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q93UQ5
- Elsewhere: RCSB PDB 4Q0U · PDBe 4Q0U · UniProt Q93UQ5
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