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Crystal structure of rabbit ryanodine receptor 1 SPRY2 domain (1070- 1246)

Analyse Crystal structure of rabbit ryanodine receptor 1 SPRY2 domain (1070- 1246) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
4P9J
Type
protein
Length
540 residues
Chains
3
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Ryanodine receptor 1
UniProt
P11716
Pockets
2 · best druggability 0.44

Structure

x-ray diffraction · 1 distinct chain · 7% helix, 34% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
C, A, BRyanodine receptor 1protein1807% helix, 34% strandP11716

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11030.440.7820empty
2940.430.7818empty

Interfaces

2 interfaces between chains.

  • C–A · 539 Ų buried · 9 hydrogen bonds · protein-protein
  • A–B · 536 Ų buried · 10 hydrogen bonds · protein-protein

Compared structures

  • 4P9J · Crystal Structure of rabbit Ryanodine Receptor 1 SPRY2 Domain (1070-1246) · the same entry in another collection · chain C against C, TM-score 1.00

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