Research workbench
Crystal structure of rabbit ryanodine receptor 1 SPRY2 domain (1070- 1246)
Analyse Crystal structure of rabbit ryanodine receptor 1 SPRY2 domain (1070- 1246) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4P9J
- Type
- protein
- Length
- 540 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ryanodine receptor 1
- UniProt
- P11716
- Pockets
- 2 · best druggability 0.44
Structure
x-ray diffraction · 1 distinct chain · 7% helix, 34% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| C, A, B | Ryanodine receptor 1 | protein | 180 | 7% helix, 34% strand | P11716 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 103 | 0.44 | 0.78 | 20 | empty |
| 2 | 94 | 0.43 | 0.78 | 18 | empty |
Interfaces
2 interfaces between chains.
- C–A · 539 Ų buried · 9 hydrogen bonds · protein-protein
- A–B · 536 Ų buried · 10 hydrogen bonds · protein-protein
Compared structures
- 4P9J · Crystal Structure of rabbit Ryanodine Receptor 1 SPRY2 Domain (1070-1246) · the same entry in another collection · chain C against C, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P11716
- Elsewhere: RCSB PDB 4P9J · PDBe 4P9J · UniProt P11716
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