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GDP-bound stalkless-mxa

Analyse GDP-bound stalkless-mxa in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4P4T
Type: protein
Length: 335 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Interferon-induced GTP-binding protein MX1
UniProt: P20591
Ligands: GDP, SO4
Pockets: 4 · best druggability 0.65

Structure

x-ray diffraction · 1 distinct chain · 45% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Interferon-induced GTP-binding protein MX1	protein	335	45% helix, 17% strand	P20591

Ligands and binding sites

GDP · Guanosine-5'-diphosphate · ligand · chains A
SO4 · Sulfate ion · ion · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	385	0.65	0.79	47	GDP
2	165	0.43	0.74	28	empty
3	99	0.37	0.75	24	empty
4	55	0.34	0.77	16	empty

Compared structures

4P4T · GDP-bound stalkless-MxA · the same entry in another collection · chain A against A, TM-score 1.00
P20591 · AlphaFold monomer V2.0 prediction for interferon-induced GTP-binding protein MX1 (P20591) · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P20591
Elsewhere: RCSB PDB 4P4T · PDBe 4P4T · UniProt P20591

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