Research workbench

Influenza polymerase basic protein 2 (PB2) bound to 7-methyl-GTP

Analyse Influenza polymerase basic protein 2 (PB2) bound to 7-methyl-GTP in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4NCE
Type: protein
Length: 163 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Polymerase basic protein 2
UniProt: P31345
Ligands: 11H, MGT
Pockets: 1 · best druggability 0.46

Structure

x-ray diffraction · 1 distinct chain · 25% helix, 41% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Polymerase basic protein 2	protein	163	25% helix, 41% strand	P31345

Ligands and binding sites

11H · 9,10-dioxo-9,10-dihydroanthracene-2,6-disulfonic acid · ligand · 2 copies · chains A
MGT · 7N-methyl-8-hydroguanosine-5'-triphosphate · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	128	0.46	0.77	20	MGT

Compared structures

4NCE · Influenza polymerase basic protein 2 (PB2) bound to 7-methyl-GTP · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P31345
Elsewhere: RCSB PDB 4NCE · PDBe 4NCE · UniProt P31345

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.