UniProt P31345
Polymerase basic protein 2 (P31345)
Polymerase basic protein 2 (UniProt P31345): 28 experimental structures on GenesisL1, 6 ligands bound, 8 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P31345
- Protein
- Polymerase basic protein 2
- Experimental structures
- 28
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 8 · 1 record with a druggable one
Structures
28 records of P31345 in the MolNFT archive: 28 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2GMO | NMR-structure of an independently folded C-terminal domain of influenza polymerase subunit PB2 | solution nmr | A | — | — |
| 2GMO | NMR-structure of an independently folded C-terminal domain of influenza polymerase subunit PB2 | solution nmr | A | — | — |
| 2JDQ | C-terminal domain of influenza A virus polymerase PB2 subunit in complex with human importin alpha5 | x-ray diffraction | D, E | — | — |
| 2JDQ | C-terminal domain of influenza a virus polymerase PB2 subunit in complex with human importin ALPHA5 | x-ray diffraction | D, E | — | — |
| 2VQZ | Structure of the cap-binding domain of influenza virus polymerase subunit PB2 with bound m7GTP | x-ray diffraction | A, B, D, E, F | — | — |
| 2VQZ | Structure of the cap-binding domain of influenza virus polymerase subunit PB2 with bound M7GTP | x-ray diffraction | A, B, D, E, F | — | — |
| 2VY6 | Two domains from the C-terminal region of influenza A virus polymerase PB2 subunit | x-ray diffraction | A | — | — |
| 2VY6 | Two domains from the C-terminal region of influenza a virus polymerase PB2 subunit | x-ray diffraction | A | — | — |
| 2VY7 | The 627-domain from influenza A virus polymerase PB2 subunit | x-ray diffraction | A | — | — |
| 2VY7 | The 627-domain from influenza a virus polymerase PB2 subunit | x-ray diffraction | A | — | — |
| 2VY8 | The 627-domain from influenza A virus polymerase PB2 subunit with Glu- 627 | x-ray diffraction | A | — | — |
| 2VY8 | The 627-domain from influenza a virus polymerase PB2 subunit with glu-627 | x-ray diffraction | A | — | — |
| 4NCE | Influenza polymerase basic protein 2 (PB2) bound to 7-methyl-GTP | x-ray diffraction | A | — | — |
| 4NCE | Influenza polymerase basic protein 2 (PB2) bound to 7-methyl-GTP | x-ray diffraction | A | — | — |
| 4NCM | Influenza polymerase basic protein 2 (PB2) bound to a small-molecule inhibitor | x-ray diffraction | A | — | — |
| 4NCM | Influenza polymerase basic protein 2 (PB2) bound to a small-molecule inhibitor | x-ray diffraction | A | — | — |
| 4P1U | Influenza A (flu) virus polymerase basic protein 2 (PB2) bound to VX787, an azaindole inhibitor | x-ray diffraction | A | — | — |
| 4P1U | Influenza a (flu) virus polymerase basic protein 2 (PB2) bound to VX787, an azaindole inhibitor | x-ray diffraction | A | — | — |
| 4UAD | Importin alpha 7 delta IBB in complex with Influenza PB2 Nuclear Localization Domain | x-ray diffraction | E | — | — |
| 4UAD | Importin alpha 7 delta ibb in complex with influenza PB2 nuclear localization domain | x-ray diffraction | E | — | — |
| 4UAE | Importin alpha 3 delta IBB in complex with Influenza PB2 Nuclear Localization Domain | x-ray diffraction | F | — | — |
| 4UAE | Importin alpha 3 delta ibb in complex with influenza PB2 nuclear localization domain | x-ray diffraction | F | — | — |
| 4UAF | Importin alpha 1 delta IBB in complex with Influenza PB2 nuclear localization domain | x-ray diffraction | E | — | — |
| 4UAF | Importin alpha 1 delta ibb in complex with influenza PB2 nuclear localization domain | x-ray diffraction | E | — | — |
| 6EUV | Structure of the midlink and cap-binding domains of influenza A polymerase PB2 subunit with a bound… | x-ray diffraction | A, C, F, I | 21G, NI | — |
| 6EUV | Structure of the midlink and cap-binding domains of influenza a polymerase PB2 subunit with a bound… | x-ray diffraction | A, C, F, I | 21G, NI | — |
| 6EUY | Structure of the midlink and cap-binding domains of influenza a polymerase PB2 subunit with a bound… | x-ray diffraction | A, B, C | BYB, SO4 | — |
| 7XME | Structure of Influenza A virus polymerase basic protein 2 (PB2) with an azazindole derivative | x-ray diffraction | A, B, C, D | IOD, GIH | 8 (best 0.69) |
Ligands
- 21G · (2S,3S)-3-[[5-fluoranyl-2-(5-fluoranyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid · in 2 records
- NI · Nickel (II) ion · in 2 records
- BYB · (2~{S},3~{S})-3-[[5-fluoranyl-2-(5-fluoranyl-1~{H}-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid · in 1 record
- GIH · (2~{S},3~{S})-3-[[5-dimethoxyphosphoryl-4-(5-fluoranyl-1~{H}-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid · in 1 record
- IOD · Iodide ion · in 1 record
- SO4 · Sulfate ion · in 1 record
Elsewhere
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