Research workbench
Crystal structure of leubat (DELTA13 mutant) in complex with fluvoxamine
Analyse Crystal structure of leubat (DELTA13 mutant) in complex with fluvoxamine in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4MM9
- Type
- protein
- Length
- 499 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transporter
- UniProt
- O67854
- Ligands
- FVX, NA
- Pockets
- 5 · best druggability 0.78
Structure
x-ray diffraction · 1 distinct chain · 77% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transporter | protein | 499 | 77% helix, 1% strand | O67854 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 780 | 0.78 | 0.82 | 67 | NA, FVX |
| 2 | 84 | 0.55 | 0.86 | 18 | empty |
| 3 | 85 | 0.46 | 0.80 | 15 | empty |
| 4 | 67 | 0.33 | 0.75 | 13 | empty |
| 5 | 51 | 0.28 | 0.74 | 8 | empty |
Compared structures
- 4MM9 · Crystal structure of LeuBAT (delta13 mutant) in complex with fluvoxamine · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O67854
- Elsewhere: RCSB PDB 4MM9 · PDBe 4MM9 · UniProt O67854
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.