Research workbench
The X-ray Crystal Structure of the Trichoderma harzianum Endoglucanase 3 from family GH12
Analyse The X-ray Crystal Structure of the Trichoderma harzianum Endoglucanase 3 from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4H7M
- Type
- protein
- Length
- 451 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.068
- Source
- Trichoderma harzianum
- Molecule
- Endo-1,4-beta-glucanase
- EC
- 3.2.1.4
- UniProt
- I3RY46
- Pockets
- 4 · best druggability 0.54
Structure
x-ray diffraction · resolution 2.068 · 2 distinct chains · 7% helix, 55% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Endo-1,4-beta-glucanase (EC 3.2.1.4) | protein | 226 | 7% helix, 55% strand | I3RY46 |
| B | Endo-1,4-beta-glucanase (EC 3.2.1.4) | protein | 225 | 8% helix, 54% strand | I3RY46 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 216 | 0.54 | 0.78 | 28 | empty |
| 2 | 186 | 0.47 | 0.75 | 27 | empty |
| 3 | 181 | 0.46 | 0.75 | 34 | empty |
| 4 | 152 | 0.45 | 0.76 | 37 | empty |
Interfaces
1 interface between chains.
- A–B · 386 Ų buried · 10 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 4H7M · The X-ray crystal structure of the trichoderma harzianum endoglucanase 3 from family GH12 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt I3RY46
- Elsewhere: RCSB PDB 4H7M · PDBe 4H7M · UniProt I3RY46
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.