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Crystal structure of the B-DNA hexamer ggcgcc with spermine

Analyse Crystal structure of the B-DNA hexamer ggcgcc with spermine in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
1F6C
Type
DNA
Length
30 nucleotides
Chains
5
Method
x-ray diffraction
Collection
MolNFT v2 / PDB Bank
Contract
0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner
0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution
2.7
Molecule
DNA (5'-D(*GP*GP*CP*GP*CP*C)-3')
Ligands
SPM

Structure

x-ray diffraction · resolution 2.7 · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
A, B, C, D, EDNA (5'-D(*GP*GP*CP*GP*CP*C)-3')dna6——

Ligands and binding sites

  • SPM · Spermine · ligand · 2 copies · chains B, C, A, D, E

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

7 interfaces between chains.

  • B–C · 288 Ų buried · 37 hydrogen bonds · nucleic-nucleic
  • D–E · 281 Ų buried · 32 hydrogen bonds · nucleic-nucleic
  • A–D · 132 Ų buried · 2 hydrogen bonds · nucleic-nucleic
  • C–D · 131 Ų buried · 0 hydrogen bonds · nucleic-nucleic
  • B–E · 126 Ų buried · 1 hydrogen bond · nucleic-nucleic

Compared structures

  • 1F6C · Crystal structure of the B-DNA hexamer ggcgcc with spermine · the same entry in another collection · chain A against A, TM-score 1.00

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