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Crystal structure of the N-terminal signalling domain of human Dhh without calcium

Analyse Crystal structure of the N-terminal signalling domain of human Dhh without… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2WFQ
Type: protein
Length: 164 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 1.85
Source: HOMO SAPIENS
Molecule: Desert hedgehog protein N-product
UniProt: O43323
Ligands: ZN, SO4
Pockets: 1 · best druggability 0.31

Structure

x-ray diffraction · resolution 1.85 · 1 distinct chain · 30% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Desert hedgehog protein N-product	protein	164	30% helix, 19% strand	O43323

Ligands and binding sites

ZN · Zinc ion · metal · chains A
SO4 · Sulfate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	61	0.31	0.75	15	empty

Compared structures

2WFQ · Crystal structure of the N-terminal signalling domain of human dhh without calcium · the same entry in another collection · chain A against A, TM-score 1.00
O43323 · AlphaFold monomer V2.0 prediction for desert hedgehog protein (O43323) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O43323
Elsewhere: RCSB PDB 2WFQ · PDBe 2WFQ · UniProt O43323

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